Jalil Mammadguluzadeh was born in Nakhchivan, 1866. he gor his first education in Religious school. After a year studied in Russian – Turkic school in Nakhchivan. Later entered Gori Pedagogical Seminary. He graduated from seminary in 1887. He was involved in teaching at rural schools in Bash-Norashen, Ulukhanli, Nehram and other towns and villages of the Erivan Governorate. Mirze Jalil wrote "Çay dəstgahı" in 1889. It is allegoric play. It is valuable play to create the impression about sympathy of Mirze Jalil to satire and humor.
In 1898, he moved to Erivan. He had worked as translator in different offices and as advocate in the law-court. In 1903 he came to Tbilisi where he met Məhəmməd ağa Şahtaxtlı and he became a columnist for the local Sharqi-Rus newspaper.
In 1906 he became the editor of the new Molla Nasraddin illustrated satirical magazine. Molla Nasreddin was a political and social weekly in Azeri Turkish, which was published from 7 April 1906 until 1917 in Tbilisi (340 issues), in 1921 in Tabriz (8 issues), and from 1922 to 1931 in Baku (400 issues). Mammadguluzadeh wrote under different satirical names such as – Qārinqoli, Serteq, Dala. He is mostly remembered for his short stories such as “Pocht qutusu” (The post box), “Usta Zeynal” (Master Zeynal), “Iranda hurriyat (Democracy in Iran), and “Saqqali uşaq” (The bearded child).
Mammadguluzadeh was instrumental in every aspect of the journal right from the outset. He had written both in Russian and Azeri Turkish in liberal newspapers of Tiblisi
Jalil Mammadguluzadeh married Azerbaijani philanthropist and feminist-activist Hamida Javanshir. He died in Baku, in 1932.
Jalil Mammadguluzadeh wrote in various genres, including short stories, novels, essays, and dramatics. "Danabaş kəndinin əhvalatları" ("Eşşəyin itməkliyi"), "Qurbanəli bəy", "Usta Zeynal", "Poçt qutusu", "Bəlkə də qaytardılar", "İranda hürriyyət", "Zırrama", "Saqqallı uşaq", "Kişmiş oyunu", "Konsulun arvadı", "Yan tütəyi", "Pirverdinin xoruzu", "Xanın təsbehi", "Taxıl həkimi", "Quzu" and etc. In addition to his mother tongue Azeri, he was also proficient in Persian and Russian languages.
In 1928 he has written drama "Qəmərin toyu" but after completing the drama author has burnt the play.